RefSeq Gene
 

RefSeq Gene DDAH2

RefSeq: NM_013974.1   Status: Reviewed
Description: Homo sapiens dimethylarginine dimethylaminohydrolase 2 (DDAH2), mRNA.
CCDS: CCDS4718.1
CDS: 3' complete
OMIM: 604744
Entrez Gene: 23564
PubMed on Gene: DDAH2
PubMed on Product: N(G) N(G)-dimethylarginine dimethylaminohydrolase 2
GeneCards: DDAH2
AceView: DDAH2


Summary of DDAH2

This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF070667.1, AF087894.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025083 [ECO:0000348] ##Evidence-Data-END##


mRNA/Genomic Alignments

The alignment you clicked on is first in the table below.
BROWSER | SIZE IDENTITY CHROMOSOME  STRAND    START     END              QUERY      START  END  TOTAL
-----------------------------------------------------------------------------------------------------
browser |  1331  100.0%  6_mann_hap4     -   3037707   3040929             NM_013974     1  1331  1351
browser |  1331   99.9%          6     -  31694817  31698039             NM_013974     1  1331  1351
browser |  1331  100.0%  6_cox_hap2     -   3204434   3207656             NM_013974     1  1331  1351
browser |  1331  100.0%  6_dbb_hap3     -   2980386   2983608             NM_013974     1  1331  1351
browser |  1331  100.0%  6_mcf_hap5     -   3074500   3077722             NM_013974     1  1331  1351
browser |  1331  100.0%  6_qbl_hap6     -   2988447   2991669             NM_013974     1  1331  1351
browser |  1331  100.0%  6_ssto_hap7     -   3025634   3028856             NM_013974     1  1331  1351

View details of parts of alignment within browser window
.

Position: chr6_mann_hap4:3037707-3040929
Genomic Size: 3223
Strand: -
Gene Symbol: DDAH2
CDS Start: complete
CDS End: complete

Position: chr6_cox_hap2:3204434-3207656
Genomic Size: 3223
Strand: -
Gene Symbol: DDAH2
CDS Start: complete
CDS End: complete

Position: chr6:31694817-31698039
Band: 6p21.33
Genomic Size: 3223
Strand: -
Gene Symbol: DDAH2
CDS Start: complete
CDS End: complete

Position: chr6_mcf_hap5:3074500-3077722
Genomic Size: 3223
Strand: -
Gene Symbol: DDAH2
CDS Start: complete
CDS End: complete

Position: chr6_ssto_hap7:3025634-3028856
Genomic Size: 3223
Strand: -
Gene Symbol: DDAH2
CDS Start: complete
CDS End: complete

Position: chr6_dbb_hap3:2980386-2983608
Genomic Size: 3223
Strand: -
Gene Symbol: DDAH2
CDS Start: complete
CDS End: complete

Position: chr6_qbl_hap6:2988447-2991669
Genomic Size: 3223
Strand: -
Gene Symbol: DDAH2
CDS Start: complete
CDS End: complete

Links to sequence:

View table schema

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Data last updated: 2014-06-14

Description

The RefSeq Genes track shows known human protein-coding and non-protein-coding genes taken from the NCBI RNA reference sequences collection (RefSeq). The data underlying this track are updated daily.

Display Conventions and Configuration

This track follows the display conventions for gene prediction tracks. The color shading indicates the level of review the RefSeq record has undergone: predicted (light), provisional (medium), reviewed (dark).

The item labels and display colors of features within this track can be configured through the controls at the top of the track description page.

  • Label: By default, items are labeled by gene name. Click the appropriate Label option to display the accession name instead of the gene name, show both the gene and accession names, or turn off the label completely.
  • Codon coloring: This track contains an optional codon coloring feature that allows users to quickly validate and compare gene predictions. To display codon colors, select the genomic codons option from the Color track by codons pull-down menu. For more information about this feature, go to the Coloring Gene Predictions and Annotations by Codon page.
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Methods

RefSeq RNAs were aligned against the human genome using BLAT. Those with an alignment of less than 15% were discarded. When a single RNA aligned in multiple places, the alignment having the highest base identity was identified. Only alignments having a base identity level within 0.1% of the best and at least 96% base identity with the genomic sequence were kept.

Credits

This track was produced at UCSC from RNA sequence data generated by scientists worldwide and curated by the NCBI RefSeq project.

References

Kent WJ. BLAT - the BLAST-like alignment tool. Genome Res. 2002 Apr;12(4):656-64. PMID: 11932250; PMC: PMC187518

Pruitt KD, Tatusova T, Maglott DR. NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D501-4. PMID: 15608248; PMC: PMC539979