Human Gene C6orf10 (uc021zqb.1) Description and Page Index
  Description: Homo sapiens chromosome 6 open reading frame 10 (C6orf10), mRNA.
Transcript (Including UTRs)
   Position: chr6_mann_hap4:3,603,328-3,682,495 Size: 79,168 Total Exon Count: 26 Strand: -
Coding Region
   Position: chr6_mann_hap4:3,603,594-3,682,322 Size: 78,729 Coding Exon Count: 26 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
  Press "+" in the title bar above to open this section.

-  Comments and Description Text from UniProtKB
DESCRIPTION: SubName: Full=Uncharacterized protein C6orf10;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: C6orf10
CDC HuGE Published Literature: C6orf10
Positive Disease Associations: Arthritis, Juvenile Rheumatoid , Arthritis, Rheumatoid , Asthma , Diabetes Mellitus, Type 1 , Diabetic Nephropathies , Drug-Induced Liver Injury , Graves Disease , Lupus Erythematosus, Systemic , Multiple Sclerosis , Psoriasis
Related Studies:
  1. Arthritis, Juvenile Rheumatoid
    Edward M Behrens et al. Arthritis and rheumatism 2008, Association of the TRAF1-C5 locus on chromosome 9 with juvenile idiopathic arthritis., Arthritis and rheumatism. [PubMed 18576341]
  2. Arthritis, Rheumatoid
    Eli A Stahl et al. Nature genetics 2010, Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci., Nature genetics. [PubMed 20453842]
  3. Asthma
    Tomomitsu Hirota et al. Nature genetics 2011, Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population., Nature genetics. [PubMed 21804548]
           more ... click here to view the complete list

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  Microarray Expression Data
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips


GNF Expression Atlas 1 Human Data on Affy U95 Chips


-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -37.90173-0.219 Picture PostScript Text
3' UTR -32.06266-0.121 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on E9PMB1
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
Jackson LabRGD    
Protein Sequence     

-  Descriptions from all associated GenBank mRNAs
  AK310230 - Homo sapiens cDNA, FLJ17272.
U60665 - Human testis specific basic protein (TSBP), complete cds.
BC034774 - Homo sapiens chromosome 6 open reading frame 10, mRNA (cDNA clone MGC:34216 IMAGE:5169157), complete cds.
AK302176 - Homo sapiens cDNA FLJ57662 complete cds.
AK225742 - Homo sapiens mRNA for Splice isoform 2 of Q5SRN2 variant, clone: TST08922.

-  Other Names for This Gene
  Alternate Gene Symbols: AK225742, E9PMB1, E9PMB1_HUMAN, NM_006781, NP_006772
UCSC ID: uc021zqb.1
RefSeq Accession: NM_006781
Protein: E9PMB1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: AK225742.1
exon count: 26CDS single in 3' UTR: no RNA size: 1740
ORF size: 1686CDS single in intron: no Alignment % ID: 99.88
txCdsPredict score: 3466.50frame shift in genome: no % Coverage: 97.82
has start codon: yes stop codon in genome: no # of Alignments: 8
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 572# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.