Human Gene LST1 (uc021zpi.1) Description and Page Index
  Description: Homo sapiens leukocyte specific transcript 1 (LST1), transcript variant 4, mRNA.
RefSeq Summary (NM_205839): The protein encoded by this gene is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:2,896,840-2,899,570 Size: 2,731 Total Exon Count: 5 Strand: +
Coding Region
   Position: chr6_mann_hap4:2,897,961-2,899,337 Size: 1,377 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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+  Comments and Description Text from UniProtKB
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-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: LST1
CDC HuGE Published Literature: LST1
Positive Disease Associations: Psoriasis
Related Studies:
  1. Psoriasis
    , , . [PubMed 0]

+  Comparative Toxicogenomics Database (CTD)
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-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
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GNF Expression Atlas 1 Human Data on Affy U95 Chips

      
    
     
      
    
    
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+  mRNA Secondary Structure of 3' and 5' UTRs
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+  Protein Domain and Structure Information
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
Jackson LabRGD    
Protein Sequence     
Alignment     

-  Descriptions from all associated GenBank mRNAs
  BX647293 - Homo sapiens mRNA; cDNA DKFZp781G1336 (from clone DKFZp781G1336).
AF000425 - Homo sapiens LST1 mRNA, cLST1/A splice variant, complete cds.
AF000424 - Homo sapiens LST1 mRNA, cLST1/C splice variant, complete cds.
AF000426 - Homo sapiens LST1 mRNA, cLST1/E splice variant, complete cds.
BC103855 - Homo sapiens leukocyte specific transcript 1, mRNA (cDNA clone MGC:119006 IMAGE:40003000), complete cds.
BC103856 - Homo sapiens leukocyte specific transcript 1, mRNA (cDNA clone MGC:119007 IMAGE:40003004), complete cds.
Y18486 - Homo sapiens mRNA for LST-1/J protein.
Y18487 - Homo sapiens mRNA for LST-1/K protein.
Y18488 - Homo sapiens mRNA for LST-1/L protein, partial.
Y18489 - Homo sapiens mRNA for LST-1/M protein.
Y18490 - Homo sapiens mRNA for LST-1/N protein.
AY852265 - Homo sapiens LST1/O mRNA, complete cds, alternatively spliced.
AY852266 - Homo sapiens LST1/P mRNA, complete cds, alternatively spliced.
DQ099382 - Homo sapiens leukocyte specific transcript 1 mRNA, complete cds, alternatively spliced.

+  Other Names for This Gene
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-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_205839.2
exon count: 5CDS single in 3' UTR: no RNA size: 769
ORF size: 294CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 571.00frame shift in genome: no % Coverage: 99.35
has start codon: yes stop codon in genome: no # of Alignments: 8
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
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