Human Gene AGPAT1 (uc011hcs.2) Description and Page Index
  Description: Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 1 (AGPAT1), transcript variant 2, mRNA.
RefSeq Summary (NM_032741): This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:3,478,807-3,488,712 Size: 9,906 Total Exon Count: 7 Strand: -
Coding Region
   Position: chr6_mann_hap4:3,479,877-3,482,097 Size: 2,221 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsPathwaysOther Names
Model InformationMethods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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+  Comments and Description Text from UniProtKB
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-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: AGPAT1
CDC HuGE Published Literature: AGPAT1
Positive Disease Associations: Diabetes Mellitus, Type 1 , Macular Degeneration , Phospholipids , Psoriasis
Related Studies:
  1. Diabetes Mellitus, Type 1
    , , . [PubMed 0]
  2. Macular Degeneration
    , , . [PubMed 0]
  3. Macular Degeneration
    , , . [PubMed 0]
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+  Comparative Toxicogenomics Database (CTD)
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+  Microarray Expression Data
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+  mRNA Secondary Structure of 3' and 5' UTRs
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+  Protein Domain and Structure Information
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+  Orthologous Genes in Other Species
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+  Descriptions from all associated GenBank mRNAs
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-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
hsa00561 - Glycerolipid metabolism
hsa00564 - Glycerophospholipid metabolism
hsa01100 - Metabolic pathways

-  Other Names for This Gene
  Alternate Gene Symbols: A2BFI5, G15, NM_032741, NP_116130, PLCA_HUMAN, Q5BL03, Q99943
UCSC ID: uc011hcs.2
RefSeq Accession: NM_032741
Protein: Q99943 (aka PLCA_HUMAN