Human Gene EGFL8 (uc011hcm.1) Description and Page Index
  Description: Homo sapiens EGF-like-domain, multiple 8 (EGFL8), transcript variant 2, non-coding RNA.
Transcript (Including UTRs)
   Position: chr6_mann_hap4:3,475,209-3,479,137 Size: 3,929 Total Exon Count: 9 Strand: +
Coding Region
   Position: chr6_mann_hap4:3,476,770-3,478,560 Size: 1,791 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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+  Comments and Description Text from UniProtKB
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-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: EGFL8
CDC HuGE Published Literature: EGFL8
Positive Disease Associations: Macular Degeneration , Phospholipids
Related Studies:
  1. Macular Degeneration
    , , . [PubMed 0]
  2. Macular Degeneration
    , , . [PubMed 0]
  3. Macular Degeneration
    , , . [PubMed 0]
           more ... click here to view the complete list

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
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GNF Expression Atlas 1 Human Data on Affy U95 Chips

      
    
     
      
    
    
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -30.10105-0.287 Picture PostScript Text
3' UTR -201.55577-0.349 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

+  Protein Domain and Structure Information
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+  Orthologous Genes in Other Species
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-  Descriptions from all associated GenBank mRNAs
  AK307427 - Homo sapiens cDNA, FLJ97375.
AF020544 - Homo sapiens inactive palmitoyl-protein thioesterase-2i (PPT2) mRNA, complete cds.
AK296648 - Homo sapiens cDNA FLJ52513 complete cds, highly similar to Lysosomal thioesterase PPT2 precursor (EC 3.1.2.-).
AK290473 - Homo sapiens cDNA FLJ78536 complete cds, highly similar to Homo sapiens inactive palmitoyl-protein thioesterase-2i (PPT2) mRNA.
AK292729 - Homo sapiens cDNA FLJ75166 complete cds, highly similar to Homo sapiens palmitoyl-protein thioesterase 2 (PPT2), transcriptvariant 3, mRNA.
BC052591 - Homo sapiens EGF-like-domain, multiple 8, mRNA (cDNA clone MGC:59719 IMAGE:6295477), complete cds.
BC035574 - Homo sapiens EGF-like-domain, multiple 8, mRNA (cDNA clone MGC:44938 IMAGE:5247785), complete cds.
AY358139 - Homo sapiens clone DNA178658 NG3 (UNQ8752) mRNA, complete cds.
AK126457 - Homo sapiens cDNA FLJ44493 fis, clone UTERU2035452, highly similar to Homo sapiens NG3.
AK309657 - Homo sapiens cDNA, FLJ99698.
AB190520 - Homo sapiens mRNA for VE-statin2, complete cds.
CU690110 - Synthetic construct Homo sapiens gateway clone IMAGE:100016679 5' read EGFL8 mRNA.
CU690920 - Synthetic construct Homo sapiens gateway clone IMAGE:100022393 5' read EGFL8 mRNA.
HQ448382 - Synthetic construct Homo sapiens clone IMAGE:100071809; CCSB013658_04 palmitoyl-protein thioesterase 2 (PPT2) gene, encodes complete protein.

+  Other Names for This Gene
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+  Gene Model Information
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+  Methods, Credits, and Use Restrictions
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