C2-deficiency gene Poncet D et al. 1982, Association of the C2-deficiency gene (C2*QO) with the C4A*4 C4B*2 genes., Journal of immunogenetics. 1982 Apr;9(2):127-32.
Carcinoma, Hepatocellular Robert J Clifford et al. Hepatology (Baltimore, Md.) 2010, Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma., Hepatology (Baltimore, Md.).
Cross Infection|Pneumonia, Ventilator-Associated|Wounds and Injuries John A Morris , et al. The Journal of trauma 2009 66(5):1265-70; discussion 1270-2, Genetic variation in complement component 2 of the classical complement pathway is associated with increased mortality and infection: a study of 627 patients with trauma., The Journal of trauma 2009 66(5):1265-70; discussion 1270-2.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on B4DQI1
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.