Human Gene MSH5 (uc011hbh.2) Description and Page Index
  Description: Homo sapiens mutS homolog 5 (E. coli) (MSH5), transcript variant 3, mRNA.
RefSeq Summary (NM_172166): This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:3,050,615-3,058,094 Size: 7,480 Total Exon Count: 10 Strand: +
Coding Region
   Position: chr6_mann_hap4:3,051,134-3,058,094 Size: 6,961 Coding Exon Count: 9 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr6_mann_hap4:3,050,615-3,058,094)mRNA (may differ from genome)Protein (834 aa)
Gene SorterGenome BrowserProtein FASTATable SchemaBioGPSCGAP
EnsemblEntrez GeneExonPrimerGeneCardsGeneNetworkGepis Tissue