Human Gene LY6G6C (uc011hat.2) Description and Page Index
  Description: Homo sapiens lymphocyte antigen 6 complex, locus G6C (LY6G6C), mRNA.
RefSeq Summary (NM_025261): LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: BC036302.1, BM716645.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025083, ERS025089 [ECO:0000350] ##Evidence-Data-END##
Transcript (Including UTRs)
   Position: chr6_mann_hap4:3,029,314-3,032,400 Size: 3,087 Total Exon Count: 3 Strand: -
Coding Region
   Position: chr6_mann_hap4:3,029,762-3,032,345 Size: 2,584 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
  Press "+" in the title bar above to open this section.

+  Comments and Description Text from UniProtKB
  Press "+" in the title bar above to open this section.

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: LY6G6C
CDC HuGE Published Literature: LY6G6C
Positive Disease Associations: Lupus Erythematosus, Systemic
Related Studies:
  1. Lupus Erythematosus, Systemic
    , , . [PubMed 0]

+  Comparative Toxicogenomics Database (CTD)
  Press "+" in the title bar above to open this section.

-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
Ratios
      
      
      
     
    
     
Absolute
      
       
      
      
     
    
Ratios
      
       
      
      
     
    
Absolute
   
     
     
Ratios
   
     
     
Absolute

GNF Expression Atlas 1 Human Data on Affy U95 Chips

      
    
     
      
    
    
Ratios
      
    
     
      
    
    
Absolute
      
      
      
Ratios
      
      
      
Absolute

+  mRNA Secondary Structure of 3' and 5' UTRs
  Press "+" in the title bar above to open this section.

+  Protein Domain and Structure Information
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Jackson Lab     
Protein Sequence     
Alignment     

-  Descriptions from all associated GenBank mRNAs
  BC036302 - Homo sapiens lymphocyte antigen 6 complex, locus G6C, mRNA (cDNA clone MGC:24882 IMAGE:4776231), complete cds.
AY359119 - Homo sapiens clone DNA96878 G6C (UNQ1947) mRNA, complete cds.
AJ315533 - Homo sapiens mRNA for LY6G6C protein, splice variant 1.
AJ315534 - Homo sapiens mRNA for truncated LY6G6C protein, splice variant 2.

+  Other Names for This Gene
  Press "+" in the title bar above to open this section.

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_025261.2
exon count: 3CDS single in 3' UTR: no RNA size: 932
ORF size: 378CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 956.00frame shift in genome: no % Coverage: 94.53
has start codon: yes stop codon in genome: no # of Alignments: 7
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.