Human Gene ABHD16A (uc011hae.2) Description and Page Index
  Description: Homo sapiens abhydrolase domain containing 16A (ABHD16A), transcript variant 3, non-coding RNA.
RefSeq Summary (NM_021160): A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is thought to be involved in some aspects of immunity. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:2,997,616-3,013,741 Size: 16,126 Total Exon Count: 20 Strand: -
Coding Region
   Position: chr6_mann_hap4:2,997,879-3,002,554 Size: 4,676 Coding Exon Count: 13 

Page IndexSequence and LinksUniProtKB CommentsCTDMicroarrayRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Abhydrolase domain-containing protein 16A; EC=3.-.-.-; AltName: Full=HLA-B-associated transcript 5; AltName: Full=Protein G5;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
SIMILARITY: Belongs to the AB hydrolase superfamily. ABHD16 family.
SEQUENCE CAUTION: Sequence=CAI17808.2; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAI18401.2; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAM26084.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAM45793.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  Microarray Expression Data
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips


-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -328.60987-0.333 Picture PostScript Text
3' UTR -67.86263-0.258 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR026604 - ABHD16

Pfam Domains:
PF00561 - alpha/beta hydrolase fold

SCOP Domains:
53474 - alpha/beta-Hydrolases

ModBase Predicted Comparative 3D Structure on O95870
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
Jackson LabRGD    
Protein Sequence     

-  Descriptions from all associated GenBank mRNAs
  AK297235 - Homo sapiens cDNA FLJ50806 complete cds, highly similar to HLA-B-associated transcript 5.
AF193047 - Homo sapiens PP199 mRNA, complete cds.
BC031839 - Homo sapiens HLA-B associated transcript 5, mRNA (cDNA clone MGC:24847 IMAGE:4931559), complete cds.
AK055255 - Homo sapiens cDNA FLJ30693 fis, clone FCBBF2000685, highly similar to HLA-B-associated transcript 5.
AK023194 - Homo sapiens cDNA FLJ13132 fis, clone NT2RP3003008.
AK025398 - Homo sapiens cDNA: FLJ21745 fis, clone COLF5038.
AK001207 - Homo sapiens cDNA FLJ10345 fis, clone NT2RM2000984.
AK289469 - Homo sapiens cDNA FLJ77631 complete cds, highly similar to Homo sapiens HLA-B associated transcript 5 (BAT5), mRNA.
AK297712 - Homo sapiens cDNA FLJ53140 complete cds, highly similar to HLA-B-associated transcript 5.
DQ891325 - Synthetic construct clone IMAGE:100003955; FLH171100.01X; RZPDo839F01100D HLA-B associated transcript 5 (BAT5) gene, encodes complete protein.
DQ894509 - Synthetic construct Homo sapiens clone IMAGE:100008969; FLH171096.01L; RZPDo839F0199D HLA-B associated transcript 5 (BAT5) gene, encodes complete protein.
AB529165 - Synthetic construct DNA, clone: pF1KE1036, Homo sapiens BAT5 gene for HLA-B associated transcript 5, without stop codon, in Flexi system.
AK308573 - Homo sapiens cDNA, FLJ98614.
AK303496 - Homo sapiens cDNA FLJ54975 complete cds.
CU689246 - Synthetic construct Homo sapiens gateway clone IMAGE:100019865 5' read BAT5 mRNA.

-  Other Names for This Gene
  Alternate Gene Symbols: A2BEY3, ABHGA_HUMAN, B7Z4R6, BAT5, G5, NG26, NM_021160, NP_066983, NR_033488, O95870, PP199, Q5SRR1, Q5SRR2, Q8WYH0, Q9NW33
UCSC ID: uc011hae.2
RefSeq Accession: NM_021160
Protein: O95870 (aka ABHGA_HUMAN