Human Gene LY6G5C (uc011had.1) Description and Page Index
  Description: Homo sapiens lymphocyte antigen 6 complex, locus G5C (LY6G5C), mRNA.
RefSeq Summary (NM_025262): LY6G5C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: AJ315542.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025082, ERS025083 [ECO:0000350] ##Evidence-Data-END##
Transcript (Including UTRs)
   Position: chr6_mann_hap4:2,987,351-2,994,707 Size: 7,357 Total Exon Count: 4 Strand: -

Page IndexSequence and LinksGenetic AssociationsCTDMicroarrayOther Species
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: LY6G5C
CDC HuGE Published Literature: LY6G5C
Positive Disease Associations: Macular Degeneration
Related Studies:
  1. Macular Degeneration
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  Microarray Expression Data
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips


-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Descriptions from all associated GenBank mRNAs
  AJ315542 - Homo sapiens mRNA for LY6G5C protein, isoform B (LY6G5C gene), splice variant 3.
AJ315543 - Homo sapiens mRNA for truncated LY6G5C protein (LY6G5C gene), splice variant 4.
AJ315544 - Homo sapiens mRNA for truncated LY6G5C protein (LY6G5C gene), splice variant 5.
AJ315540 - Homo sapiens mRNA for truncated LY6G5C protein, (LY6G5C gene), splice variant 1.
AJ315541 - Homo sapiens mRNA for partial LY6G5C protein, isoform A (LY6G5C gene), splice variant 2.
BC141637 - Synthetic construct Homo sapiens clone IMAGE:100014648, MGC:175332 lymphocyte antigen 6 complex, locus G5C (LY6G5C) mRNA, encodes complete protein.
BC140342 - Synthetic construct Homo sapiens clone IMAGE:100014310, MGC:173188 lymphocyte antigen 6 complex, locus G5C (LY6G5C) mRNA, encodes complete protein.
AB463847 - Synthetic construct DNA, clone: pF1KB7241, Homo sapiens LY6G5C gene for lymphocyte antigen 6 complex, locus G5C, without stop codon, in Flexi system.

-  Other Names for This Gene
  Alternate Gene Symbols: AJ315541
UCSC ID: uc011had.1
RefSeq Accession: NM_025262

-  Gene Model Information
category: nearCoding nonsense-mediated-decay: no RNA accession: AJ315541.1
exon count: 4CDS single in 3' UTR: no RNA size: 677
ORF size: 0CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 404.50frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 7
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.