Human Gene LY6G5B (uc011haa.1) Description and Page Index
Description: Homo sapiens lymphocyte antigen 6 complex, locus G5B (LY6G5B), mRNA. RefSeq Summary (NM_021221): LY6G5B belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: AJ315545.1, AK289364.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025081, ERS025093 [ECO:0000348] ##Evidence-Data-END## Transcript (Including UTRs) Position: chr6_mann_hap4:2,981,618-2,983,117 Size: 1,500 Total Exon Count: 3 Strand: + Coding Region Position: chr6_mann_hap4:2,981,618-2,982,949 Size: 1,332 Coding Exon Count: 3
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q8NDX9
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.