Human Gene BAG6 (uc011gzj.2) Description and Page Index
  Description: Homo sapiens BCL2-associated athanogene 6 (BAG6), transcript variant 1, mRNA.
RefSeq Summary (NM_004639): This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:2,949,688-2,963,366 Size: 13,679 Total Exon Count: 25 Strand: -
Coding Region
   Position: chr6_mann_hap4:2,949,791-2,962,429 Size: 12,639 Coding Exon Count: 24 

Page IndexSequence and LinksUniProtKB CommentsCTDMicroarrayRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
  Press "+" in the title bar above to open this section.

+  Comments and Description Text from UniProtKB
  Press "+" in the title bar above to open this section.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
Ratios
      
      
      
     
    
     
Absolute
      
       
      
      
     
    
Ratios
      
       
      
      
     
    
Absolute
   
     
     
Ratios
   
     
     
Absolute

GNF Expression Atlas 1 Human Data on Affy U95 Chips

      
    
     
      
    
    
Ratios
      
    
     
      
    
    
Absolute
      
      
      
Ratios
      
      
      
Absolute

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -140.20314-0.446 Picture PostScript Text
3' UTR -19.40103-0.188 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

+  Protein Domain and Structure Information
  Press "+" in the title bar above to open this section.

+  Orthologous Genes in Other Species
  Press "+" in the title bar above to open this section.

-  Descriptions from all associated GenBank mRNAs
  AK302695 - Homo sapiens cDNA FLJ60983 complete cds, highly similar to Large proline-rich protein BAT3.
BX647244 - Homo sapiens mRNA; cDNA DKFZp686L0653 (from clone DKFZp686L0653).
BC003133 - Homo sapiens HLA-B associated transcript 3, mRNA (cDNA clone MGC:3619 IMAGE:2957896), complete cds.
M33519 - Human HLA-B-associated transcript 3 (BAT3) mRNA, complete cds.
AK304879 - Homo sapiens cDNA FLJ61584 complete cds, highly similar to Large proline-rich protein BAT3.
AB384971 - Synthetic construct DNA, clone: pF1KB4636, Homo sapiens BAT3 gene for large proline-rich protein BAT3, complete cds, without stop codon, in Flexi system.
CU678390 - Synthetic construct Homo sapiens gateway clone IMAGE:100020517 5' read BAT3 mRNA.
DQ591812 - Homo sapiens piRNA piR-58924, complete sequence.

+  Other Names for This Gene
  Press "+" in the title bar above to open this section.

+  Gene Model Information
  Press "+" in the title bar above to open this section.

+  Methods, Credits, and Use Restrictions
  Press "+" in the title bar above to open this section.