Human Gene PRRC2A (uc011gze.1) Description and Page Index
Description: Homo sapiens proline-rich coiled-coil 2A (PRRC2A), transcript variant 1, mRNA. RefSeq Summary (NM_080686): A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]. Transcript (Including UTRs) Position: chr6_mann_hap4:2,931,334-2,945,933 Size: 14,600 Total Exon Count: 14 Strand: +
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
BC050408 - Homo sapiens, clone IMAGE:6197872, mRNA. AB210034 - Homo sapiens mRNA for C6orf21 variant protein, partial cds, clone: hj06729. AK309774 - Homo sapiens cDNA, FLJ99815. AK302756 - Homo sapiens cDNA FLJ56810 complete cds, highly similar to Large proline-rich protein BAT2. BC042295 - Homo sapiens HLA-B associated transcript 2, mRNA (cDNA clone MGC:48688 IMAGE:5555847), complete cds. BC060668 - Homo sapiens HLA-B associated transcript 2, mRNA (cDNA clone MGC:57530 IMAGE:6471026), complete cds. BC032134 - Homo sapiens HLA-B associated transcript 2, mRNA (cDNA clone IMAGE:4653409), partial cds. M33509 - Human HLA-B-associated transcript 2 (BAT2) mRNA, complete cds. AB384680 - Synthetic construct DNA, clone: pF1KB0056, Homo sapiens BAT2 gene for large proline-rich protein BAT2, complete cds, without stop codon, in Flexi system. AF075059 - Homo sapiens full length insert cDNA YO70F05. AK297210 - Homo sapiens cDNA FLJ56600 complete cds, highly similar to Large proline-rich protein BAT2. CR749245 - Homo sapiens mRNA; cDNA DKFZp686D09175 (from clone DKFZp686D09175). BC030127 - Homo sapiens, Similar to HLA-B associated transcript 2, clone IMAGE:3345434, mRNA, partial cds. AK298584 - Homo sapiens cDNA FLJ56925 complete cds, highly similar to Large proline-rich protein BAT2.