Human Gene LST1 (uc011gyw.2) Description and Page Index
  Description: Homo sapiens leukocyte specific transcript 1 (LST1), transcript variant 6, mRNA.
RefSeq Summary (NM_001166538): The protein encoded by this gene is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:2,897,861-2,899,570 Size: 1,710 Total Exon Count: 3 Strand: +
Coding Region
   Position: chr6_mann_hap4:2,897,961-2,899,337 Size: 1,377 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
  Press "+" in the title bar above to open this section.

+  Comments and Description Text from UniProtKB
  Press "+" in the title bar above to open this section.

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: LST1
CDC HuGE Published Literature: LST1
Positive Disease Associations: Psoriasis
Related Studies:
  1. Psoriasis
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
Ratios
      
      
      
     
    
     
Absolute
      
       
      
      
     
    
Ratios
      
       
      
      
     
    
Absolute
   
     
     
Ratios
   
     
     
Absolute

GNF Expression Atlas 1 Human Data on Affy U95 Chips

      
    
     
      
    
    
Ratios
      
    
     
      
    
    
Absolute
      
      
      
Ratios
      
      
      
Absolute

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -21.40100-0.214 Picture PostScript Text
3' UTR -52.30233-0.224 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

+  Protein Domain and Structure Information
  Press "+" in the title bar above to open this section.

+  Orthologous Genes in Other Species
  Press "+" in the title bar above to open this section.

-  Descriptions from all associated GenBank mRNAs
  BX647293 - Homo sapiens mRNA; cDNA DKFZp781G1336 (from clone DKFZp781G1336).
AF000425 - Homo sapiens LST1 mRNA, cLST1/A splice variant, complete cds.
AF000424 - Homo sapiens LST1 mRNA, cLST1/C splice variant, complete cds.
AF000426 - Homo sapiens LST1 mRNA, cLST1/E splice variant, complete cds.
BC103855 - Homo sapiens leukocyte specific transcript 1, mRNA (cDNA clone MGC:119006 IMAGE:40003000), complete cds.
BC103856 - Homo sapiens leukocyte specific transcript 1, mRNA (cDNA clone MGC:119007 IMAGE:40003004), complete cds.
Y18486 - Homo sapiens mRNA for LST-1/J protein.
Y18487 - Homo sapiens mRNA for LST-1/K protein.
Y18488 - Homo sapiens mRNA for LST-1/L protein, partial.
Y18489 - Homo sapiens mRNA for LST-1/M protein.
Y18490 - Homo sapiens mRNA for LST-1/N protein.
AY852265 - Homo sapiens LST1/O mRNA, complete cds, alternatively spliced.
AY852266 - Homo sapiens LST1/P mRNA, complete cds, alternatively spliced.
DQ099382 - Homo sapiens leukocyte specific transcript 1 mRNA, complete cds, alternatively spliced.

+  Other Names for This Gene
  Press "+" in the title bar above to open this section.

+  Gene Model Information
  Press "+" in the title bar above to open this section.

+  Methods, Credits, and Use Restrictions
  Press "+" in the title bar above to open this section.