Human Gene POU5F1 (uc011gwl.2) Description and Page Index
  Description: Homo sapiens POU class 5 homeobox 1 (POU5F1), transcript variant 1, mRNA.
RefSeq Summary (NM_002701): This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:2,480,458-2,486,814 Size: 6,357 Total Exon Count: 5 Strand: -
Coding Region
   Position: chr6_mann_hap4:2,480,722-2,486,760 Size: 6,039 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr6_mann_hap4:2,480,458-2,486,814)mRNA (may differ from genome)Protein (360 aa)
Gene SorterGenome BrowserProtein FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
Gepis Tissue