Human Gene SFTA2 (uc011gvr.2) Description and Page Index
  Description: Homo sapiens surfactant associated 2 (SFTA2), mRNA.
Transcript (Including UTRs)
   Position: chr6_mann_hap4:2,247,208-2,248,033 Size: 826 Total Exon Count: 3 Strand: -
Coding Region
   Position: chr6_mann_hap4:2,247,346-2,247,954 Size: 609 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
  Press "+" in the title bar above to open this section.

-  Comments and Description Text from UniProtKB
  ID: SFTA2_HUMAN
DESCRIPTION: RecName: Full=Surfactant-associated protein 2; AltName: Full=Surfactant-associated protein G; Flags: Precursor;
SUBCELLULAR LOCATION: Secreted (Probable).

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: SFTA2
CDC HuGE Published Literature: SFTA2
Positive Disease Associations: Behcet Syndrome
Related Studies:
  1. Behcet Syndrome
    Elaine F Remmers et al. Nature genetics 2010, , Nature genetics. [PubMed 20622878]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -26.9079-0.341 Picture PostScript Text
3' UTR -52.50138-0.380 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR028198 - SFTA2

ModBase Predicted Comparative 3D Structure on Q6UW10
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AY102070 - Homo sapiens surfactant associated protein G mRNA, partial sequence.
BC039677 - Homo sapiens surfactant associated 2, mRNA (cDNA clone MGC:50178 IMAGE:5186107), complete cds.
AY359057 - Homo sapiens clone DNA59854 GSGL541 (UNQ541) mRNA, complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: A2ABK7, A2ACH1, B7ZCJ7, NM_205854, NP_995326, Q6UW10, SFTA2_HUMAN, SFTPG, UNQ541/PRO1098
UCSC ID: uc011gvr.2
RefSeq Accession: NM_205854
Protein: Q6UW10 (aka SFTA2_HUMAN