Human Gene PPP1R10 (uc011gte.3) Description and Page Index
  Description: Homo sapiens protein phosphatase 1, regulatory subunit 10 (PPP1R10), transcript variant 1, mRNA.
RefSeq Summary (NM_002714): This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:1,916,249-1,933,156 Size: 16,908 Total Exon Count: 20 Strand: -
Coding Region
   Position: chr6_mann_hap4:1,917,398-1,925,793 Size: 8,396 Coding Exon Count: 18 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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+  Comments and Description Text from UniProtKB
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-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: PPP1R10
CDC HuGE Published Literature: PPP1R10
Positive Disease Associations: Behcet Syndrome
Related Studies:
  1. Behcet Syndrome
    Elaine F Remmers et al. Nature genetics 2010, , Nature genetics. [PubMed 20622878]
  2. Behcet Syndrome
    Elaine F Remmers et al. Nature genetics 2010, , Nature genetics. [PubMed 20622878]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
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GNF Expression Atlas 1 Human Data on Affy U95 Chips

      
    
     
      
    
    
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -190.91616-0.310 Picture PostScript Text
3' UTR -402.221149-0.350 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

+  Protein Domain and Structure Information
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+  Orthologous Genes in Other Species
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-  Descriptions from all associated GenBank mRNAs
  Y13247 - Homo sapiens fb19 mRNA.
AJ544537 - Homo sapiens mRNA for protein phospahatase nuclear targeting subunit (CAT53 gene).
BC150310 - Homo sapiens cDNA clone IMAGE:8860444.
BC136294 - Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 10, mRNA (cDNA clone MGC:167904 IMAGE:9020281), complete cds.
BC005267 - Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 10, mRNA (cDNA clone IMAGE:3683864), partial cds.
AK307406 - Homo sapiens cDNA, FLJ97354.

+  Other Names for This Gene
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+  Gene Model Information
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+  Methods, Credits, and Use Restrictions
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