Human Gene TRIM26 (uc011gsd.1) Description and Page Index
  Description: Homo sapiens tripartite motif containing 26 (TRIM26), transcript variant 1, mRNA.
RefSeq Summary (NM_003449): The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:1,514,942-1,521,040 Size: 6,099 Total Exon Count: 3 Strand: -
Coding Region
   Position: chr6_mann_hap4:1,514,942-1,515,379 Size: 438 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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+  Comments and Description Text from UniProtKB
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-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: TRIM26
CDC HuGE Published Literature: TRIM26
Positive Disease Associations: Behcet Syndrome , Lupus Erythematosus, Systemic , Multiple Sclerosis , Schizophrenia
Related Studies:
  1. Behcet Syndrome
    Elaine F Remmers et al. Nature genetics 2010, , Nature genetics. [PubMed 20622878]
  2. Behcet Syndrome
    Elaine F Remmers et al. Nature genetics 2010, , Nature genetics. [PubMed 20622878]
  3. Behcet Syndrome
    Elaine F Remmers et al. Nature genetics 2010, , Nature genetics. [PubMed 20622878]
           more ... click here to view the complete list

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
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GNF Expression Atlas 1 Human Data on Affy U95 Chips

      
    
     
      
    
    
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -75.81249-0.304 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

+  Protein Domain and Structure Information
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+  Orthologous Genes in Other Species
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-  Descriptions from all associated GenBank mRNAs
  BC021115 - Homo sapiens tripartite motif-containing 26, mRNA (cDNA clone IMAGE:5094007), with apparent retained intron.
BC032297 - Homo sapiens tripartite motif-containing 26, mRNA (cDNA clone MGC:40232 IMAGE:4938971), complete cds.
BC024039 - Homo sapiens tripartite motif-containing 26, mRNA (cDNA clone MGC:12710 IMAGE:3954669), complete cds.
U09825 - Human acid finger protein mRNA, complete cds.
AK314782 - Homo sapiens cDNA, FLJ95652.
CU689318 - Synthetic construct Homo sapiens gateway clone IMAGE:100019819 5' read TRIM26 mRNA.

+  Other Names for This Gene
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+  Gene Model Information
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+  Methods, Credits, and Use Restrictions
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