Human Gene TRIM31 (uc011grq.2) Description and Page Index
  Description: Homo sapiens tripartite motif containing 31 (TRIM31), mRNA.
RefSeq Summary (NM_007028): The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus. Its function has not been identified. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF230386.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025083, ERS025084 [ECO:0000350] ##Evidence-Data-END##
Transcript (Including UTRs)
   Position: chr6_mann_hap4:1,369,234-1,379,420 Size: 10,187 Total Exon Count: 9 Strand: -
Coding Region
   Position: chr6_mann_hap4:1,369,873-1,379,135 Size: 9,263 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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+  Comments and Description Text from UniProtKB
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-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: TRIM31
CDC HuGE Published Literature: TRIM31
Positive Disease Associations: Behcet Syndrome , Cardiomegaly , Psoriasis
Related Studies:
  1. Behcet Syndrome
    Elaine F Remmers et al. Nature genetics 2010, , Nature genetics. [PubMed 20622878]
  2. Cardiomegaly
    Afshin Parsa et al. Clinical and translational science 2011, Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality., Clinical and translational science. [PubMed 21348951]
  3. Psoriasis
    , , . [PubMed 0]
           more ... click here to view the complete list

+  Comparative Toxicogenomics Database (CTD)
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-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
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GNF Expression Atlas 1 Human Data on Affy U95 Chips

      
    
     
      
    
    
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+  mRNA Secondary Structure of 3' and 5' UTRs
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+  Protein Domain and Structure Information
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Jackson Lab     
Protein Sequence     
Alignment     

-  Descriptions from all associated GenBank mRNAs
  BC016866 - Homo sapiens tripartite motif-containing 31, mRNA (cDNA clone IMAGE:3849550), complete cds.
AF230386 - Homo sapiens tripartite motif protein TRIM31 alpha mRNA, complete cds.
AF230387 - Homo sapiens tripartite motif protein TRIM31 beta mRNA, complete cds.
BC017017 - Homo sapiens tripartite motif-containing 31, mRNA (cDNA clone MGC:8918 IMAGE:3846513), complete cds.
AK222729 - Homo sapiens mRNA for tripartite motif protein 31 isoform alpha variant, clone: COL09060.
X81006 - H.sapiens HCG I mRNA.
AK290270 - Homo sapiens cDNA FLJ75322 complete cds, highly similar to Homo sapiens tripartite motif-containing 31, transcript variant 1, mRNA.
BT006675 - Homo sapiens tripartite motif-containing 31 mRNA, complete cds.
DQ894616 - Synthetic construct Homo sapiens clone IMAGE:100009076; FLH176955.01L; RZPDo839B05123D tripartite motif-containing 31 (TRIM31) gene, encodes complete protein.
AB527928 - Synthetic construct DNA, clone: pF1KB0962, Homo sapiens TRIM31 gene for tripartite motif-containing 31, without stop codon, in Flexi system.
Y07828 - H.sapiens mRNA for RING protein.
AB303153 - Homo sapiens TRIM31 mRNA for tripartite motif-containing 31 gamma, complete cds.
CU677795 - Synthetic construct Homo sapiens gateway clone IMAGE:100019339 5' read TRIM31 mRNA.

+  Other Names for This Gene
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+  Gene Model Information
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+  Methods, Credits, and Use Restrictions
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