Human Gene PPP1R11 (uc011grm.2) Description and Page Index
  Description: Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 11 (PPP1R11), mRNA.
RefSeq Summary (NM_021959): This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1. The gene is located within the major histocompatibility complex class I region on chromosome 6. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X81003.1, BQ067250.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025081, ERS025082 [ECO:0000348] ##Evidence-Data-END##
Transcript (Including UTRs)
   Position: chr6_mann_hap4:1,333,524-1,336,701 Size: 3,178 Total Exon Count: 4 Strand: +

Page IndexSequence and LinksGenetic AssociationsCTDMicroarrayOther Species
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
  Press "+" in the title bar above to open this section.

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: PPP1R11
CDC HuGE Published Literature: PPP1R11
Positive Disease Associations: Multiple Sclerosis
Related Studies:
  1. Multiple Sclerosis
    Sergio E Baranzini et al. Human molecular genetics 2009, Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis., Human molecular genetics. [PubMed 19010793]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  Microarray Expression Data
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips


GNF Expression Atlas 1 Human Data on Affy U95 Chips


-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Descriptions from all associated GenBank mRNAs
  AK310593 - Homo sapiens cDNA, FLJ17635.
AK313175 - Homo sapiens cDNA, FLJ93673, Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit11 (PPP1R11), transcript variant 1, mRNA.
X81003 - Homo sapiens HCG V mRNA.
BC102010 - Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 11, mRNA (cDNA clone MGC:125743 IMAGE:40029469), complete cds.
BC102011 - Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 11, mRNA (cDNA clone MGC:125742 IMAGE:40029466), complete cds.
BC104750 - Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 11, mRNA (cDNA clone MGC:125741 IMAGE:40029465), complete cds.
BC003144 - Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 11, mRNA (cDNA clone MGC:3857 IMAGE:2823116), complete cds.
AF070599 - Homo sapiens clone 24451 mRNA sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: AK310593
UCSC ID: uc011grm.2
RefSeq Accession: NM_021959

-  Gene Model Information
category: nearCoding nonsense-mediated-decay: no RNA accession: AK310593.1
exon count: 4CDS single in 3' UTR: no RNA size: 981
ORF size: 0CDS single in intron: no Alignment % ID: 99.69
txCdsPredict score: 393.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 8
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.