Human Gene PPP1R11 (uc011grl.2) Description and Page Index
  Description: Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 11 (PPP1R11), mRNA.
RefSeq Summary (NM_021959): This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1. The gene is located within the major histocompatibility complex class I region on chromosome 6. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X81003.1, BQ067250.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025081, ERS025082 [ECO:0000348] ##Evidence-Data-END##
Transcript (Including UTRs)
   Position: chr6_mann_hap4:1,333,524-1,336,701 Size: 3,178 Total Exon Count: 3 Strand: +
Coding Region
   Position: chr6_mann_hap4:1,333,781-1,335,676 Size: 1,896 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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+  Comments and Description Text from UniProtKB
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-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: PPP1R11
CDC HuGE Published Literature: PPP1R11
Positive Disease Associations: Multiple Sclerosis
Related Studies:
  1. Multiple Sclerosis
    Sergio E Baranzini et al. Human molecular genetics 2009, Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis., Human molecular genetics. [PubMed 19010793]

+  Comparative Toxicogenomics Database (CTD)
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-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
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GNF Expression Atlas 1 Human Data on Affy U95 Chips

      
    
     
      
    
    
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -101.47257-0.395 Picture PostScript Text
3' UTR -304.141025-0.297 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

+  Protein Domain and Structure Information
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+  Orthologous Genes in Other Species
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+  Descriptions from all associated GenBank mRNAs
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-  Other Names for This Gene
  Alternate Gene Symbols: HCGV, NM_021959, NP_068778, O60927, PP1RB_HUMAN, TCTE5
UCSC ID: uc011grl.2
RefSeq Accession: NM_021959
Protein: O60927 (aka PP1RB_HUMAN