Human Gene HLA-G (uc011gqj.1) Description and Page Index
  Description: Homo sapiens major histocompatibility complex, class I, G (HLA-G), mRNA.
RefSeq Summary (NM_002127): HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC021708.2, X17273.1 [ECO:0000331] ##Evidence-Data-END##
Transcript (Including UTRs)
   Position: chr6_mann_hap4:1,095,942-1,099,228 Size: 3,287 Total Exon Count: 6 Strand: +
Coding Region
   Position: chr6_mann_hap4:1,095,951-1,098,488 Size: 2,538 Coding Exon Count: 5 

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RNA StructureProtein StructureOther SpeciesmRNA DescriptionsPathwaysOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr6_mann_hap4:1,095,942-1,099,228)mRNA (may differ from genome)Protein (246 aa)
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