Human Gene MOG (uc011gph.2) Description and Page Index
  Description: Homo sapiens myelin oligodendrocyte glycoprotein (MOG), transcript variant alpha6, mRNA.
RefSeq Summary (NM_001170418): The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:927,718-943,106 Size: 15,389 Total Exon Count: 7 Strand: +
Coding Region
   Position: chr6_mann_hap4:927,947-941,919 Size: 13,973 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDMicroarray
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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+  Comments and Description Text from UniProtKB
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-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: MOG
CDC HuGE Published Literature: MOG
Positive Disease Associations: Behcet Syndrome
Related Studies:
  1. Behcet Syndrome
    Elaine F Remmers et al. Nature genetics 2010, , Nature genetics. [PubMed 20622878]
  2. Behcet Syndrome
    Elaine F Remmers et al. Nature genetics 2010, , Nature genetics. [PubMed 20622878]

+  Comparative Toxicogenomics Database (CTD)
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+  Microarray Expression Data
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+  mRNA Secondary Structure of 3' and 5' UTRs
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-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007110 - Ig-like_dom
IPR013783 - Ig-like_fold
IPR013106 - Ig_V-set
IPR003596 - Ig_V-set_subgr
IPR016663 - Myelin-oligodendrocyte_glycop

Protein Data Bank (PDB) 3-D Structure

1Q70
- Model Chimera
Chimera help

ModBase Predicted Comparative 3D Structure on Q16653
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+  Orthologous Genes in Other Species
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+  Descriptions from all associated GenBank mRNAs
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-  Other Names for This Gene
  Alternate Gene Symbols: E9PGF0, E9PGF0_HUMAN, NM_001170418, NP_001163889
UCSC ID: uc011gph.2
RefSeq Accession: NM_001170418
Protein: Q16653 (aka MOG_HUMAN