Human Gene GABBR1 (uc011goz.1) Description and Page Index
  Description: Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), transcript variant 1, mRNA.
RefSeq Summary (NM_001470): Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:879,403-903,154 Size: 23,752 Total Exon Count: 14 Strand: -
Coding Region
   Position: chr6_mann_hap4:879,507-903,154 Size: 23,648 Coding Exon Count: 14 

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Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr6_mann_hap4:879,403-903,154)mRNA (may differ from genome)Protein (578 aa)
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