Human Gene OR2H1 (uc011gon.1) Description and Page Index
  Description: Homo sapiens olfactory receptor, family 2, subfamily H, member 1 (OR2H1), mRNA.
Transcript (Including UTRs)
   Position: chr6_mann_hap4:730,515-734,950 Size: 4,436 Total Exon Count: 3 Strand: +
Coding Region
   Position: chr6_mann_hap4:732,515-733,465 Size: 951 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
  Press "+" in the title bar above to open this section.

+  Comments and Description Text from UniProtKB
  Press "+" in the title bar above to open this section.

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: OR2H1
CDC HuGE Published Literature: OR2H1
Positive Disease Associations: Cholesterol, HDL , Lupus Erythematosus, Systemic
Related Studies:
  1. Cholesterol, HDL
    Sekar Kathiresan et al. BMC medical genetics 2007, A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study., BMC medical genetics. [PubMed 17903299]
    Using a 100K genome-wide scan, we have generated a set of putative associations for common sequence variants and lipid phenotypes. Validation of selected hypotheses in additional samples did not identify any new loci underlying variability in blood lipids. Lack of replication may be due to inadequate statistical power to detect modest quantitative trait locus effects (i.e., <1% of trait variance explained) or reduced genomic coverage of the 100K array. GWAS in FHS using a denser genome-wide genotyping platform and a better-powered replication strategy may identify novel loci underlying blood lipids.
  2. Lupus Erythematosus, Systemic
    , , . [PubMed 0]

+  Comparative Toxicogenomics Database (CTD)
  Press "+" in the title bar above to open this section.

+  mRNA Secondary Structure of 3' and 5' UTRs
  Press "+" in the title bar above to open this section.

+  Protein Domain and Structure Information
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AJ459844 - Homo sapiens mRNA for olfactory receptor (6M1-16 gene), 5'UTR variant 2.
BC036097 - Homo sapiens cDNA clone IMAGE:5299043, containing frame-shift errors.
BC048991 - Homo sapiens olfactory receptor, family 2, subfamily H, member 1, mRNA (cDNA clone MGC:57430 IMAGE:5271584), complete cds.
AK127984 - Homo sapiens cDNA FLJ46099 fis, clone TESTI2022323, highly similar to Olfactory receptor 2H1.
AJ459838 - Homo sapiens mRNA for olfactory receptor (HS6M1-16 gene), 5'UTR exon E1.
AJ459840 - Homo sapiens mRNA for olfactory receptor (6M1-16 gene), exon E variant 2.
AJ459843 - Homo sapiens mRNA for olfactory receptor (6M1-16 gene), 5'UTR variant 1.
AJ459845 - Homo sapiens mRNA for olfactory receptor (6M1-16 gene), 5'UTR variant 1.
AJ459846 - Homo sapiens mRNA for olfactory receptor (6M1-16 gene), 5'UTR variant 2.
AB463959 - Synthetic construct DNA, clone: pF1KB7129, Homo sapiens OR2H1 gene for olfactory receptor, family 2, subfamily H, member 1, without stop codon, in Flexi system.
CU690598 - Synthetic construct Homo sapiens gateway clone IMAGE:100020861 5' read OR2H1 mRNA.
HQ447990 - Synthetic construct Homo sapiens clone IMAGE:100071358; CCSB010743_01 olfactory receptor, family 2, subfamily H, member 1 (OR2H1) gene, encodes complete protein.
AJ459847 - Homo sapiens mRNA for olfactory receptor (6M1-16 gene).
AJ459849 - Homo sapiens mRNA for olfactory receptor (6M1-16 gene), 3'UTR exon B.
AJ459850 - Homo sapiens mRNA for olfactory receptor (6M1-16 gene), 3'UTR exon C.

+  Other Names for This Gene
  Press "+" in the title bar above to open this section.

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AK127984.1
exon count: 3CDS single in 3' UTR: no RNA size: 2130
ORF size: 951CDS single in intron: no Alignment % ID: 99.95
txCdsPredict score: 1703.50frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 8
has end codon: yes retained intron: yes # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.