Human Gene OR14J1 (uc011gof.2) Description and Page Index
  Description: Homo sapiens olfactory receptor, family 14, subfamily J, member 1 (OR14J1), mRNA.
RefSeq Summary (NM_030946): Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].
Transcript (Including UTRs)
   Position: chr6_mann_hap4:577,912-578,877 Size: 966 Total Exon Count: 1 Strand: +
Coding Region
   Position: chr6_mann_hap4:577,912-578,877 Size: 966 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDProtein Structure
Other SpeciesmRNA DescriptionsPathwaysOther NamesModel InformationMethods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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-  Comments and Description Text from UniProtKB
  ID: O14J1_HUMAN
DESCRIPTION: RecName: Full=Olfactory receptor 14J1; AltName: Full=Hs6M1-28; AltName: Full=Olfactory receptor 5U1; AltName: Full=Olfactory receptor OR6-25;
FUNCTION: Odorant receptor (Potential).
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
WEB RESOURCE: Name=Human Olfactory Receptor Data Exploratorium (HORDE); URL="http://bip.weizmann.ac.il/cgi-bin/HORDE/showGene.pl?key=symbol&value=OR14J1";

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: OR14J1
CDC HuGE Published Literature: OR14J1

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000276 - GPCR_Rhodpsn
IPR017452 - GPCR_Rhodpsn_7TM
IPR000725 - Olfact_rcpt

Pfam Domains:
PF00001 - 7 transmembrane receptor (rhodopsin family)

SCOP Domains:
81321 - Family A G protein-coupled receptor-like

ModBase Predicted Comparative 3D Structure on Q9UGF5
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Jackson Lab     
Protein Sequence     
Alignment     

-  Descriptions from all associated GenBank mRNAs
  BC136905 - Homo sapiens olfactory receptor, family 14, subfamily J, member 1, mRNA (cDNA clone MGC:168519 IMAGE:9020896), complete cds.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
hsa04740 - Olfactory transduction

-  Other Names for This Gene
  Alternate Gene Symbols: A2BEC2, B0V078, NM_030946, NP_112208, O14J1_HUMAN, OR5U1, Q5ST27, Q9UGF5
UCSC ID: uc011gof.2
RefSeq Accession: NM_030946
Protein: Q9UGF5 (aka O14J1_HUMAN