Human Gene ZNF311 (uc011gny.1) Description and Page Index
  Description: Homo sapiens zinc finger protein 311 (ZNF311), mRNA.
Transcript (Including UTRs)
   Position: chr6_mann_hap4:265,995-275,392 Size: 9,398 Total Exon Count: 6 Strand: -
Coding Region
   Position: chr6_mann_hap4:266,179-270,698 Size: 4,520 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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-  Comments and Description Text from UniProtKB
  ID: ZN311_HUMAN
DESCRIPTION: RecName: Full=Zinc finger protein 311; AltName: Full=Zinc finger protein zfp-31;
FUNCTION: May be involved in transcriptional regulation.
SUBCELLULAR LOCATION: Nucleus (Probable).
SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family.
SIMILARITY: Contains 14 C2H2-type zinc fingers.
SIMILARITY: Contains 1 KRAB domain.
SEQUENCE CAUTION: Sequence=AAB16812.1; Type=Frameshift; Positions=396, 408;

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database: ZNF311
CDC HuGE Published Literature: ZNF311
Positive Disease Associations: Lupus Erythematosus, Systemic
Related Studies:
  1. Lupus Erythematosus, Systemic
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -170.80555-0.308 Picture PostScript Text
3' UTR -23.80184-0.129 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001909 - Krueppel-associated_box
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

Pfam Domains:
PF00096 - Zinc finger, C2H2 type

SCOP Domains:
48695 - Multiheme cytochromes
109640 - KRAB domain (Kruppel-associated box, Pfam 01352)
57667 - C2H2 and C2HC zinc fingers
57889 - Cysteine-rich domain
57903 - FYVE/PHD zinc finger

ModBase Predicted Comparative 3D Structure on Q5JNZ3
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AL833166 - Homo sapiens mRNA; cDNA DKFZp686I2118 (from clone DKFZp686I2118).
AK289881 - Homo sapiens cDNA FLJ76000 complete cds, highly similar to Homo sapiens zinc finger protein 311 (ZNF311), mRNA.
BC136745 - Homo sapiens zinc finger protein 311, mRNA (cDNA clone MGC:168358 IMAGE:9020735), complete cds.
BC144385 - Homo sapiens cDNA clone IMAGE:9052906.
BC144386 - Homo sapiens cDNA clone IMAGE:9052907.
U71600 - Human zinc finger protein zfp31 (zf31) mRNA, partial cds.

-  Other Names for This Gene
  Alternate Gene Symbols: A2BFK5, B0S7Y4, BC144386, Q5JNZ3, Q92971, ZFP31, ZN311_HUMAN
UCSC ID: uc011gny.1
RefSeq Accession: NM_001010877
Protein: Q5JNZ3 (aka ZN311_HUMAN