Human Gene PTK2 (uc003yvq.3) Description and Page Index
  Description: Homo sapiens protein tyrosine kinase 2 (PTK2), transcript variant 2, mRNA.
RefSeq Summary (NM_005607): This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010].
Transcript (Including UTRs)
   Position: chr8:141,668,481-141,856,421 Size: 187,941 Total Exon Count: 26 Strand: -
Coding Region
   Position: chr8:141,669,565-141,756,954 Size: 87,390 Coding Exon Count: 14