Human Gene SULF1 (uc003xyi.1) Description and Page Index
  Description: Homo sapiens sulfatase 1 (SULF1), transcript variant 4, mRNA.
RefSeq Summary (NM_001128204): This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].
Transcript (Including UTRs)
   Position: chr8:70,540,007-70,573,147 Size: 33,141 Total Exon Count: 6 Strand: +
Coding Region
   Position: chr8:70,553,052-70,571,557 Size: 18,506 Coding Exon Count: 2