Human Gene DPYSL2 (uc003xfb.2) Description and Page Index
  Description: Homo sapiens dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2, mRNA.
RefSeq Summary (NM_001386): This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].
Transcript (Including UTRs)
   Position: chr8:26,435,340-26,515,693 Size: 80,354 Total Exon Count: 14 Strand: +
Coding Region
   Position: chr8:26,435,771-26,513,222 Size: 77,452 Coding Exon Count: 14 

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MicroarrayRNA StructureProtein StructureOther SpeciesmRNA DescriptionsPathways
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Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr8:26,435,340-26,515,693)mRNA (may differ from genome)Protein (572 aa)
Gene SorterGenome BrowserProtein FASTAVisiGeneTable SchemaBioGPS
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Gepis TissueH-INV